Oyster Mushroom (Pleurotus ostreatus) is typically an edible mushroom. It is also a medicinal mushroom that is traditionally used for curing various diseases. The aim of the present study was to perform chemical screening and evaluate the hepatoprotective activity of powder and extracts of Pleurotus ostreatus in CCl4-induced hepatotoxic rat. The hepatoprotective efficacy of mushroom powder as well as extracts was compared with the reference drug Silymarin (Trade name Silybin, Square Pharmaceutical Ltd, Bangladesh). The level of Bilirubin, Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) were significantly decreased in Pleurotus ostreatus powder as well as extracts-treated hepatotoxic rats while concentration of total Protein and serum Albumin were significantly increased.
KEYWORDS: Extracts, Hepatotoxicity, Long Evan Rats, Pleurotus ostreatus, Powder.
31-Aug-2024
