Manuscript Detail

Antidiabetic efficiency of Trigonella foenum-graecum in combination with sitagliptin on streptozotocin induced diabetic rats.

A combination of a plant extract used in conventional diabetes treatment and an oral hypoglycemic medication has been studied to see if it has an anti-diabetic effect as the anti-diabetic medications available on the market today have side effects, toxicity, and even treatment resistance. To investigate the effect, oral hypoglycemic drug sitagliptin, seed extract of Trigonella foenum-graecum and both of them combined were studied on glycemic control parameters, lipid profile and hepatoprotective effects. The blood glucose level, TC, TG, HDL, LDL, serum ALT (SGPT) and AST (SGOT) were measured using diagnostic kits.

Key words: Sitagliptin, Trigonella foenum-graecum, Diabetes, hypoglycemic, Combination therapy.

Comments

Md.Rifat Hasan Shemul

Mar 14 2023 , 09:16 PM

Thanks

Md. Mahafuj Rahman

Feb 20 2024 , 04:38 PM

Thanks

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