Staphylococcus aureus is recognized as a major cause of persistent nosocomial and community acquired infection and has become a global health concern. The aim of the retrospective study is to establish the incidence of Staphylococcus aureus in suppurative lesions and its antibiotic sensitivity pattern to various antibiotics in this locality. Fifty-two isolates of Staphylococcus aureus were obtained from 182 different clinical specimens between January and December 2013 from the patients who admitted in the Khwaja Yunus Ali Medical College Hospital. All isolates were confirmed by standard bacteriological procedures in the Microbiology Laboratory of the hospital. Antibiotic sensitivity pattern was carried out by disc diffusion method. The highest number of pathogens were isolated from pus (37) with the overall isolation rate of 28.52%. Males (51.92%) were more infected than females (48.08%). The age group with the highest number of isolates in male and female was 16-30 years. Females between this age group were more vulnerable to the pathogen than males. Antibiotics amikacin and tobramycin were found 100% susceptible to the isolates. The overall sensitivity pattern of Staphylococcus aureus to the following antibiotics: amoxiclav, carbenicillin, gentamycin, ceftriaxone, cotrimoxaxole, imipenem, and meropenem were (92.59%), (82.35%), (94.44%), (93.75%), (80%), (87.50%), (85.71%) respectively. The least susceptible antibiotics were azithromycin, followed by cefixime, erythromycin, and amoxicillin with the sensitivity rate less 50% each.
Keywords: Staphylococcus aureus, Antibiotics, Suppurative infection, Susceptibility, Clinical isolate
28-Feb-2025
