Oral bacterial infection is one the most common diseases caused by enormously diverse and complex oral cavity microflora consisting of around 1000 bacterial communities. Our study was designed and enrolled to explore the etiological bacterial agents of oral infections and reveal antibiotic susceptibility patterns of pathogens. 56 diabetic and non-diabetic patients of diverse aged, males and females, were involved in the test. Swab samples were collected from the infected area inside the mouth. Pathogens were isolated from the samples growing on culture media and identified by cultural and morphological characteristics. The CLSI guideline analyzed antibiotic susceptibility patterns of the pathogens. Male patients were slightly higher than females and people ranging from 40-60 years of age were more prevalent. The number of male patients was slightly higher than female patients. Klebsiella pneumoniae (39.29%), P. aeruginosa (35.71%), E. coli (14.29%), S. marcescens (8.99%), and C. freundii (1.79%) were isolated from infected sites. Azithromycin and Ciprofloxacin were the most effective (100%) antibiotics, followed by Levofloxacin (98.21%), Imipenem (92.86%), and Erythromycin (78.57%) against the pathogens whereas Ceftazidime (91.07%), Amoxicillin (87.5%), Meropenem (80.36%) and Cefepime (75%) were found most ineffective along with 12.5% intermediate response by Erythromycin and Trimethoprim. These findings are of clinical significance that can provide adequate knowledge to dentists and physicians about the selection of antibiotics to treat oral infections where Azithromycin and Ciprofloxacin should be the preference.
Key Words: Oral Bacterial Infection, Oral Microflora, Periodontitis, Diabetic, Antibiotic Susceptibility Patterns.
28-Feb-2025
